CJC-1295

CJC-1295 without DAC is a modified analog of growth hormone-releasing hormone (GHRH) with an extended half-life compared to the native hormone. Unlike the DAC version, CJC-1295 without DAC does not bind albumin, producing a shorter, more pulse-like increase in GHRH activity — more closely approximating the body's natural pulsatile GH release.

This version is frequently selected by researchers who want to study GH secretion in a pulsatile paradigm. It is commonly studied alongside Ipamorelin to examine synergistic effects on GH release through simultaneous activation of both GHRH and GHS-R pathways.

Research Applications

• Pulsatile GH studies — Preferred over DAC version when natural GH pulse amplitude is the research focus
• GH axis combinations — Synergistic effects when paired with Ipamorelin (dual-pathway GH stimulation)
• Body composition research — GH-mediated effects on lean mass and lipolysis in animal models
• IGF-1 modulation — Downstream effects on growth factor signaling and bone density markers

Specifications

• Form: White lyophilized powder
• Purity: ≥99% (HPLC verified)
• Storage: −20°C, protected from light
• Reconstitution: Bacteriostatic water recommended